After watching this, I'm like "that's all"?
Other than a zoom in on a badly drawn pot there is not much to see here.
The animation style does not matter so much to me, but the lack of content does. Next time try to put more effort in before uploading to Newgrounds.

Voice acting could have been better. Even when you have a shitty microphone you can still get some more quality by carefully recording and using filters/volume adjustment, even using free tools like Audacity.
Like sweet21 already noted, the characters should not be transparent.
All in all it feels kind of cheap and the punchline doesn't really get through because of all the little annoyances.

It's a very small, simple game. Can be addicting if you want to beat high scores.

Coins frequently spawn at gaps, impossible to collect without losing a heart.
Speed increases in steps, with altitude 50, 150, 250, ... but this is not explained in the game and comes kind of unexpected when you first start playing.
Music fits the game, but I'm missing credits. Did you make the music yourself, if not: who did?

You should finish it, regardless of whether it is well received or not. The question is, can you
do it?
Start with better collision response, then make some more interesting levels. Lose the pills unless you find a way of incorporating them into the game, right now they are useless.

Level 38, and still no challenge. I don't have to evade boss bullets, I just keep firing at the head for like 10 seconds and that's it.
Lack of balancing makes this game a waste of time. And that's a pity, because assets are really good and I like the concept of randomly generated bosses.